How can I set defaults such as text size, fill and font so that each time I start up it remembers where I've been? Also, I've defined a few special colors but those also have to be redined each time I restart the program.

Thanks again!

Field formating like font and size can be set by Command-clicking on a field with the desired attributes.

Custom colours I don't know about, alas.

An additional note, if you do not select a field or object, ie click on an empty space on your layout, and then define the font, size, etc... then these should become the default for any new layouts and/or additions to layouts.