In my solution, I have an In-Out Board where staff names are listed. There about 5 fields on it. These names are from the Staff table and are viewed through a portal on a layout based on a Home table. This home table is basically information about the company and has one record.

The problem I'm running into is that only one person can edit one of the staff records at a time, since it is a one to many relationship (Home to Staff). All others are locked out until the user either clicks out of the portal or goes to another screen. Is there a way to allow multiple users to edit different staff records in the portal at the same time? -- Thanks

No, I believe portal would not give you the above flexibility. In my solution compared to yours. I show all the records from the home table. When the user clicks on any one of the record, I do a go to related record script to a list view staff layout.

Thanks for the tip, Sanjai. I'll see if this works for me.