Heckler

I'm having an issue trying to print out labels. Scale is set to 100% in both the layout view and the printers page setup and when I print it, it comes out of the printer (and Preview) scaled down to about 1/4 the size it is supposed to be (100%). It comes up this way no matter what printer I select (some Post Script some not). It makes no difference. Any help would be greatly appreciated.