Email via Office 365

[Greg Hains]

Good evening.

I have been sending email using Office 365 for some time now and it has worked fine.  On this particular client, MFA has been enabled - and rightly so for security reasons. However, email from FM (through O365) has stopped working. Now, I have been reading up and seen that we now use the MX name of your O365 tenancy as the SMTP server, port 587, TLS, plain password etc, yet this has not worked. I think I have tried most combinations - including "smtp.office365.com, port 25, no encryption etc. 
I have also created an "app password" for the account I wish to send from but this doesn't work either.

Whilst MFA is not new to O365, has anybody had luck making this work and if so, what did you do please?

Cheers,
Greg