I work with hfinger and helped him remedy this issue. Due to the known permissions issue within FileMaker 7 Server, I started there. I tried changing the Owner permissions to "fmserver" for the in-accessible file and they persistently would switch back to "admin" upon locking the permission.
My solution was to change the "Databases" folder permissions to: Owner: fmserver and Group: fmsadmin. Once these changes were made the databases behaved as they should.